The O-allylphenyl (AP) anomeric moiety was investigated as a new leaving group that can be activated for chemical glycosylation under a variety of conditions, through both direct and remote pathways. Differentiation between the two activation pathways was achieved in a mechanistic study. The orthogonal-type activation of the AP moiety along with common thioglycosides allows for the execution of efficient oligosaccharide assembly.
Beilstein Journal of Organic Chemistry
Premathilake, Hemali and Demchenko, Alexei, "2-Allylphenyl Glycosides as Complementary Building Blocks for Oligosaccharide and Glycoconjugate Synthesis" (2012). Chemistry & Biochemistry Faculty Works. 36.