Document Type

Article

Abstract

The interaction between nanoparticles and ultrashort laser pulses holds great interest in laser nanomedicine, introducing such possibilities as selective cell targeting to create highly localized cell damage. Two models are studied to describe the laser pulse interaction with nanoparticles in the femtosecond, picosecond, and nanosecond regimes. The first is a two-temperature model using two coupled diffusion equations: one describing the heat conduction of electrons, and the other that of the lattice. The second model is a one-temperature model utilizing a heat diffusion equation for the phonon subsystem and applying a uniform heating approximation throughout the particle volume. A comparison of the two modeling strategies shows that the two-temperature model gives a good approximation for the femtosecond mode, but fails to accurately describe the laser heating for longer pulses. On the contrary, the simpler one-temperature model provides an adequate description of the laser heating of nanoparticles in the femtosecond, picosecond, and nanosecond modes.

Publication Date

January 2008

ISSN

16876393

Publication Title

Advances in Optical Technologies

DOI

10.1155/2008/251718

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