Document Type
Article
Abstract
The cationic ruthenium allenylidene complex RRuRax −[Ru(indenyl)L(PPh3)CCCPh2]+PF6 catalyzes the etherification of secondary and tertiary propargylic alcohols in a formal nucleophilic substitution reaction utilizing primary and secondary alcohols as the nucleophiles. At a catalyst loading of only 1.1 mol%, the corresponding propargylic ether products were obtained in 9 to 73% isolated yields (18 h reaction time at 100 °C); no further additives are required. The reaction exhibits an induction period; as shown by a control reaction, the high reaction temperature may chemically change the allenylidene complex to be employed as the catalyst but does not lead to catalyst deactivation.
Publication Date
3-5-2014
Publication Title
Catalysis Communications
Volume
47
First Page
45
Last Page
48
DOI
10.1016/j.catcom.2014.01.002
Recommended Citation
Alkhaleeli, Doaa F.; Baum, Kevin J.; Rabus, Jordan M.; and Bauer, Eike B., "Etherification reactions of propargylic alcohols catalyzed by a cationic ruthenium allenylidene complex" (2014). Educator Preparation & Leadership Faculty Works. 79.
DOI: https://doi.org/10.1016/j.catcom.2014.01.002
Available at:
https://irl.umsl.edu/epir/79