Document Type

Article

Abstract

After activation by chloride abstraction utilizing NaBArF as an activator (BArF = tetrakis(3,5-bis(trifluoromethyl)phenyl)borate), a complex of the general formula [RuCl2(PHOX)2] was utilized as a catalyst in propargylic substitution reactions, where PHOX is a phosphinooxazoline ligand. Oxygen and nitrogen-centered nucleophiles could be employed in the substitution of a propargylic acetate to obtain the corresponding propargylic substitution products in 87% to 9% isolated yields (45 °C, 16 h reaction time, toluene solvent, 1–2 mol% catalyst loading, 1–2 mol% activator).

Publication Date

3-5-2018

Publication Title

Catalysis Communications

Volume

106

First Page

92

Last Page

95

DOI

10.1016/j.catcom.2017.12.014

Included in

Chemistry Commons

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