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Methods and compositions are provided for increasing or enhancing the efficacy of antibiotics, such as by increasing antimicrobial activity, against a variety of microbes by co-administration with synthetic amphiphiles, including lariat ethers and hydraphiles. Methods and compositions for overcoming antibiotic resistance are also provided.
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University of Missouri System
Gokel, George; Gokel, Michael; Negin, Saeedeh; and Patel, Mohit, "Enhancement of antibiotic efficacy" (2020). UMSL Patents. 18.