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Abstract

Compositions comprising bis(tryptophan) derivatives are provided that act as antimicrobials. Also provided are methods for reversing antibiotic resistance in a bacterium, or recovering or enhancing antimicrobial activity of an antibiotic against a variety of microbes, by co-administration with a bis(tryptophan) derivative.

Patent Number

US11213512B2

Assignee

The Curators of the University of Missouri, Columbia, MO

Application Number

16/311,441

Date Filed

6-20-2017

Issue Date

1-4-2022

Comments

11213512

Bis-amino acid based compound and use thereof

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