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Compositions comprising bis(tryptophan) derivatives are provided that act as antimicrobials. Also provided are methods for reversing antibiotic resistance in a bacterium, or recovering or enhancing antimicrobial activity of an antibiotic against a variety of microbes, by co-administration with a bis(tryptophan) derivative.
The Curators of the University of Missouri, Columbia, MO
Gokel, George; Meisel, Joseph W.; and Patel, Mohit B., "Bis-amino acid based compound and use thereof" (2022). UMSL Patents. 2.