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Abstract

Methods and compositions are provided for increasing or enhancing the efficacy of antibiotics, such as by increasing antimicrobial activity, against a variety of microbes by co-administration with synthetic amphiphiles, including lariat ethers and hydraphiles. Methods and compositions for overcoming antibiotic resistance are also provided.

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Patent Number

US10463044B2

Assignee

University of Missouri System

Application Number

US15186070

Date Filed

6-17-2016

Issue Date

11-5-2019

Molecules that inhibit efflux pumps in multi-drug resistant bacteria and uses thereof

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