Differences Between Three Inbred Mouse Strains on a Wheel-Turn Avoidance Task

Dominic Zerbolio, University of Missouri-St. Louis


C57/BL6, BALB/c and C3H mice were examined for differences in the acquisition and maintenance over sessions of wheel-turn avoidance response. The C57/BL6 s performed best and the BALB/cs worst on the first day. But the BALB/cs reached and maintained the best avoidance level and the C3Hs showed the worst maintenance. Initial day avoidance rates are viewed as related to the compatibility between the initially emitted responses of the different strains to the situation and the specific task-required response. Differential strain response to the US level are suggested as accounting for maintenance level differences.


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