Document Type
Article
Keywords
emerging technologies, nanotechnology, parenteral delivery, targeting–molecular
Abstract
Nanoporous gold (np-Au) has promising applications in therapeutic delivery. The promises arise from its high surface area-to-volume ratio, ease of tuning shape and size, ability to be modified by organic molecules including drugs, and biocompatibility. Furthermore, np-Au nanostructures can generate the photothermal effect. This effect can be used either for controlled release of drugs of therapeutic importance or for destroying cancer cells by heating locally. Despite the enormous potential, the research on the therapeutical use of the np-Au is still in its early stage. In this review, we discuss the current progress and future directions of np-Au for therapeutic applications.
Publication Date
1-1-2023
Publication Title
Metals
E-ISSN
20754701
Volume
13
Issue
1
Original Article Number
78
Rights
CC BY
DOI
10.3390/met13010078
Funding Number
GM111835
Funding Sponsor
National Institute of General Medical Sciences
Recommended Citation
Sondhi, Palak; Lingden, Dhanbir; Bhattarai, Jay K.; Demchenko, Alexei V.; and Stine, Keith J., "Applications of Nanoporous Gold in Therapy, Drug Delivery, and Diagnostics" (2023). Chemistry & Biochemistry Faculty Works. 101.
DOI: https://doi.org/10.3390/met13010078
Available at:
https://irl.umsl.edu/chemistry-faculty/101