Document Type

Article

Keywords

Carbohydrates, Glycosylation, Intramolecular reactions, Oligosaccharides

Abstract

Carbohydrate oligomers remain challenging targets for chemists due to the requirement for elaborate protecting and leaving group manipulations, functionalization, tedious purification, and sophisticated characterization. Achieving high stereocontrol in glycosylation reactions is arguably the major hurdle that chemists experience. This review article overviews methods for intramolecular glycosylation reactions wherein the facial stereoselectivity is achieved by tethering of the glycosyl donor and acceptor counterparts.

Publication Date

9-29-2017

Publication Title

Beilstein Journal of Organic Chemistry

E-ISSN

18605397

Volume

13

First Page

2028

Last Page

2048

Rights

CC BY

DOI

10.3762/bjoc.13.201

Funding Number

GM111835

Funding Sponsor

National Institute of General Medical Sciences

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