Doctor of Nursing Practice
Date of Defense
A. Laurie Vining, DNP, APRN, WHNP-BC
Jennifer Cortopassi, MMS, PA-C
Problem: Human papillomaviruses are the causative agents of >95% of cervical cancers, most oropharyngeal and anogenital cancers, yet the vaccination status of the population remains critically low despite Gardasil9 offering robust protection against HPV-related disease.
Methods: This quality improvement project utilized a descriptive, observational design to assess the effect of the HPV Encouragement Bundle, a two-step intervention to improve HPV vaccine uptake. Quantitative data was collected via retrospective chart review to assess the effect of the intervention on first-dose administration of Gardasil9 (series initiation), as well as overall Gardasil9 vaccine uptake.
Results: Following implementation, Gardasil9 first dose uptake increased from 0% to 8.45%, and overall Gardasil9 uptake increased from 0.8% to 12.68%, in pre- and post-intervention groups, respectively. A Chi-square test of independence was performed to examine the relationship between intervention groups and Gardasil9 administration. A statistically significant relationship was established between intervention groups and
Gardasil9 administration, with alpha value of .05, χ2(1) = 14.19, p < .001. Persons in the post-intervention group were more likely to be administered a dose of Gardasil9. Implications for practice: Widespread use of the HPV Encouragement Bundle is a cost-effective, inclusive intervention that could be used to improve Gardasil9 vaccine uptake.
Woll, Lauren E., "Encouraging Human Papillomavirus Vaccine Uptake: A Healthcare Improvement Project" (2023). Dissertations. 1361.
Family Practice Nursing Commons, Female Urogenital Diseases and Pregnancy Complications Commons, Male Urogenital Diseases Commons, Maternal, Child Health and Neonatal Nursing Commons, Nursing Midwifery Commons, Public Health and Community Nursing Commons, Public Health Education and Promotion Commons, Virus Diseases Commons, Women's Health Commons