The department currently has 18 regular faculty members, offering research opportunities in organic chemistry, inorganic chemistry, physical chemistry, biochemistry and nanoscience, and several adjunct professors. There are approximately 60 students in the graduate program, and there are a number of postdoctoral associates working in the department. Faculty and students occupy laboratory and office space in Benton Hall, the Research Wing of the Science Complex, and the Center for Nanoscience (CNS).

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Research from 2019

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Synthetic Ionophores as Non-Resistant Antibiotic Adjuvants, RSC Advances, George Gokel, Mohit Patel, Evan Garrad, Joseph Meisel, Saeedeh Negin, and Michael Gokel

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Selective Alteration of the Root Morphology of Arabidopsis thaliana by Synthetic Anion Transporters (SATs), Chemical Science International Journal, Mohit Patel, Evan Garrad, Steven Korb, Saeedeh Negin, Michael Gokel, Sergey Sedinkin, Shanheng Yin, and George Gokel

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The Chemistry and Biology of Cyclophostin, the Cyclipostins and Related Compounds, Molecules, Christopher Spilling

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Biosensor Applications of Electrodeposited Nanostructures, Applied Sciences (Switzerland), Keith Stine

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Nanoporous Gold and Other Related Materials, Nanomaterials, Keith Stine

Research from 2018

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Preparation, Modification, Characterization, and Biosensing Application of Nanoporous Gold Using Electrochemical Techniques, Nanomaterials, Jay Bhattarai, Dharmendra Neupane, Bishal Nepal, Vasilii Mikhaylov, Alexei Demchenko, and Keith Stine

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Conjugation of Nanomaterials and Nematic Liquid Crystals for Futuristic Applications and Biosensors, Biosensors, Thomas George, Amit Choudhary, and Guoqiang Li

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Shaping Light in Backward-Wave Nonlinear Hyperbolic Metamaterials, Photonics, Thomas George, Alexander Popov, Sergey Myslivets, Vitaly Slabko, and Victor Tkachenko

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Laser-induced Ultrafast Transport and Demagnetization at the Earliest Time: First-principles and Real-time Investigation, Journal of Physics Condensed Matter, Thomas George, G.P. Zhang, Y. Bai, and T. Jenkins

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Crystal Structures of 2-Bromo-1,1,1,3,3,3-Hexa­methyl-2-(Tri­methyl­sil­yl)Tris­ilane and 2-Bromo-1,1,1,3,3,3-Hexa­isopropyl-2-(Triiso­propyl­sil­yl)Tri­silane, Acta Crystallographica Section E: Crystallographic Communications, Eva Gulotty, Richard Staples, Shannon Biros, Peter Gaspar, Nigam Rath, and William Winchester

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The spin-forbidden a 4Σ−–X 2Π1/2 transition of GeH detected in absorption using intracavity laser spectroscopy, Journal of Chemical Physics, Jack Harms, Leah O’Brien, and James O’Brien

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LipG a Bifunctional Phospholipase/Thioesterase Involved in Mycobacterial Envelope Remodeling, Bioscience Reports, Christopher Spilling, Pierre Santucci, Vanessa Point, Isabelle Poncin, Alexandre Guy, Celine Crauste, Carole Serveau-Avesque, Jean Galano, Jean-Francois Cavalier, and Stephane Canaan

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Generating High-Order Optical and Spin Harmonics from Ferromagnetic Monolayers, Nature Communications, G.P. Zhang, M.S. Si, M. Murakami, Y.H. Bai, and Thomas George

Research from 2017

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Intramolecular Glycosylation, Beilstein Journal of Organic Chemistry, Alexei Demchenko and Xiao Jia

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Is Perpendicular Magnetic Anisotropy Essential to All-optical Ultrafast Spin Reversal in Ferromagnets?, Journal of Physics Condensed Matter, Thomas George, Y. Bai, and G.P. Zhang

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First-Principles and Model Simulation of All-Optical Spin Reversal, Physical Review B, Thomas George, G.P. Zhang, Z. Babyak, Y. Xue, and Y. Bai

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Biophysical and Computational Studies of the vCCI:vMIP-II Complex, International Journal of Molecular Sciences, Anna Nguyen, Nai-Wei Kuo, Laura Showalter, Ricardo Ramos, Cynthia Dupureur, Michael Colvin, and Patricia LiWang

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Cyclipostins and Cyclophostin Analogs as Promising Compounds in the Fight Against Tuberculosis, Scientific Reports, Phuong Nguyen, Vincent Delorme, Anaïs Bénarouche, Benjamin Martin, Rishi Paudel, Giri Gnawali, Abdeldjalil Madani, Rémy Puppo, Valérie Landry, Laurent Kremer, Priscille Brodin, Christopher Spilling, Jean-François Cavalier, and Stéphane Canaan

Research from 2016

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Ultrafast Reduction of Exchange Splitting in Ferromagnetic Nickle, Journal of Physics Condensed Matter, Thomas George, G.P. Zhang, and Y. Bai

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APP Regulates Microglial Phenotype in a Mouse Model of Alzheimer's Disease, The Journal of Neuroscience, Gunjan Manocha, Angela Floden, Keiko Rausch, Joshua Kulas, Brett McGregor, Lalida Rojanathammanee, Kelley Puig, Kendra Puig, Sanjib Karki, Michael Nichols, Diane Darland, James Porter, and Colin Combs

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A Simplified Direct Lipid Mixing Lipoplex Preparation: Comparison of Liposomal-, Dimethylsulfoxide-, and Ethanol-Based Methods, Scientific Reports, Joseph Meisel and George Gokel

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Fluselenamyl: A Novel Benzoselenazole Derivative for Pet Detection of Amyloid Plaques (Aβ) in Alzheimer's Disease, Scientific Reports, Nigam Rath, G.S.M. Sundaram, Dhruva Dhavale, Julie Prior, Ping Yan, John Cirrito, Richard Laforest, Nigel Cairns, Jin-Moo Lee, Paul Kotzbauer, and Vijay Sharma

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Characterization of WY 14,643 and Its Complex with Aldose Reductase, Scientific Reports, Michael Sawaya, Malkhey Verma, Vaishnavi Balendiran, Nigam Rath, Duilio Cascio, and Ganesaratnam Balendiran

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Interactions of two large antiviral polyamides with the long control region of HPV16., Biochimie, Elena Vasilieva, Jacquelyn Niederschulte, Yang Song, George Harris, Kevin Koeller, Puhong Liao, James Bashkin, and Cynthia Dupureur

Research from 2015

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Magnetic Spin Moment Reduction in Photoexcited Ferromagnets through Exchange Interaction Quenching: Beyond the Rigid Band Approximation, Journal of Physics Condensed Matter, Thomas George, G.P. Zhang, M. Si, and Y. Bai

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Heterogeneous Dynamics in DNA Site Discrimination by the Structurally Homologous DNA-Binding Domains of ETS-Family Transcription Factors, Nucleic Acids Research, Gaofei He, Ana Tolic, James Bashkin, and Gregory Poon

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Stereocontrolled 1,2-Cis Glycosylation as the Driving Force of Progress in Synthetic Carbohydrate Chemistry, Chemical Science, Swati Nigudkar and Alexei Demchenko

Research from 2014

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Intrinsic Delocalization during the Decay of Excitons in Polymeric Solar Cells, Polymers, Thomas George, W. Chen, D. Jiang, R. Chen, and S. Li

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2-Acylamido Analogues of N-Acetylglucosamine Prime Formation of Chitin Oligosaccharides by Yeast Chitin Synthase 2, Journal of Biological Chemistry, Jacob Gyore, Archana Parameswar, Carleigh Hebbard, Younghoon Oh, Erfei Bi, Alexei Demchenko, Neil Price, and Peter Orlean

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Structural Insights into the Interaction Between a Potent Anti-Inflammatory Protein, Viral CC Chemokine Inhibitor (vCCI), and the Human CC Chemokine, Eotaxin-1, Journal of Biological Chemistry, Nai-Wei Kuo, Yong-Guang Gao, Megan Schill, Nancy Isern, Cynthia Dupureur, and Patricia LiWang

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Relay Cross Metathesis Reactions of Vinylphosphonates, Beilstein Journal of Organic Chemistry, Raj Malla, Jeremy Ridenour, and Christopher Spilling

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A Generator-Produced Gallium-68 Radiopharmaceutical for PET Imaging of Myocardial Perfusion, PLoS ONE, Nigam Rath, Vijay Sharma, Jothilingam Sivapackiam, Scott Harpstrite, Julie Prior, Hannah Gu, and David Piwnica-Worms

Research from 2013

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DNA Damage Repair Genes Controlling Human Papillomavirus (HPV) Episome Levels Under Conditions of Stability and Extreme Instability, PLOS ONE, Terri Edwards, Thomas Vidmar, Kevin Koeller, James Bashkin, and Chris Fisher

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Electronic Two-transition-induced Enhancement of Emission Efficiency in Polymer Light-emitting Diodes, Materials, Thomas George, R.-A. Chen, C. Wang, and S. Li

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Psychosine, the Cytotoxic Sphingolipid That Accumulates in Globoid Cell Leukodystrophy, Alters Membrane Architecture, Journal of Lipid Research, Jacqueline Hawkins-Salsbury, Archana Parameswar, Xuntian Jiang, Paul Schlesinger, Ernesto Bongarzone, Daniel Ory, Alexei Demchenko, and Mark Sands

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Hydraphiles: A Rigorously Studied Class of Synthetic Channel Compounds with in Vivo Activity, International Journal of Biomedical Imaging, Saeedeh Negin, Bryan Smith, Alexandra Unger, W. Leevy, and George Gokel

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New Bis(Imino)Pyridine Complexes of Iron(II) and Iron(III), and Their Catalytic­ Activity in the Mukaiyama Aldol Reaction, Synthesis, Pushkar Shejwalkar, Nigam Rath, and Eike Bauer

Research from 2012

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Proposed Coherent Trapping of a Population of Electrons in a C60 Molecule Induced by Laser Excitation, Physical Review Letters, Thomas George and G.P. Zhang

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2-Allylphenyl Glycosides as Complementary Building Blocks for Oligosaccharide and Glycoconjugate Synthesis, Beilstein Journal of Organic Chemistry, Hemali Premathilake and Alexei Demchenko

Research from 2011

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Computational Studies of New Materials II: From Ultrafast Processes and Nanostructures to Optoelectronics, Energy Storage and Nanomedicine, Computational Studies of New Materials II: From Ultrafast Processes and Nanostructures to Optoelectronics, Energy Storage and Nanomedicine, Thomas George, D. Jelski, R. Letfullin, and G. Zhang

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The Pt2 (1,0) band of System VI in the near infrared by intracavity laser absorption spectroscopy, The Journal of Chemical Physics, Leah O'Brien and James O'Brien

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Dicarbonyldichloridobis(Trimethylphosphane)Iron(Ii)–Carbonyldichloridotris(Trimethylphosphane)Iron(Ii)–Tetrahydrofuran (1/1/2), Acta Crystallographica Section E-structure Reports Online, Nigam Rath, Meghan Stouffer, Matthew Janssen, and John Bleeke

Research from 2010

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(1E,3E)-1,4-Bis(4-Methoxyphenyl)Buta1,3-Diene, Acta Crystallographica Section E-structure Reports Online, Gopinathan Narayan, Nigam Rath, and Suresh Das

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New Chiral Phosphoramidite Complexes of Iron as Catalytic Precursors in the Oxidation of Activated Methylene Groups, Molecules, Pushkar Shejwalkar, Nigam Rath, and Eike Bauer

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2,4,6-Triphenyl­aniline, Acta Crystallographica Section E-structure Reports Online, Onome Ugono, Stephanie Cowin, and Alicia Beatty

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2,2′,5,5′-Tetra­chloro­benzidine, Acta Crystallographica Section E-structure Reports Online, Onome Ugono, Marcel Douglas, Nigam Rath, and Alicia Beatty

Research from 2009

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Catena-Poly[[(Pyridine-κN)Copper(II)]-μ3-Pyridine-2,6-Dicarboxylato-κ3O2:O2′,N,O6:O6′], Acta Crystallographica Section E-structure Reports Online, Manoj Trivedi, Daya Pandey, and Nigam Rath

Research from 2008

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Ultrashort Laser Pulse Heating of Nanoparticles: Comparison of Theoretical Approaches, Advances in Optical Technologies, Thomas George and R. Letfullin

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Laser-Induced Photon-Branched Chain Reaction in a Chemically-Active Gas-Dispersed Medium, Laser Chemistry, Thomas George, Renat Letfullin, and Galen Duree

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4-(4-Chlorophenyl)-5-[1-(4-Chlorophenyl)-2-Methyl-2-Nitropropyl]-1,2,3-Selenadiazole, Acta Crystallographica Section E-structure Reports Online, A. Marx, S. Saravanan, S. Muthusubramanian, V. Manivannan, and Nigam Rath

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Diethyl 2-[(4-Nitro­Phen­Yl)(4-Phenyl-1,2,3-Selenadiazol-5-Yl)Meth­Yl]Malonate, Acta Crystallographica Section E-structure Reports Online, A. Marx, S. Saravanan, S. Muthusubramanian, V. Manivannan, and Nigam Rath

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Dioxidobis(2-Oxo-1,2-Dihydropyridin-3-Olato)­Molybdenum(VI), Acta Crystallographica Section E-structure Reports Online, Manoj Trivedi, Daya Pandey, and Nigam Rath

Research from 2006

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Exchange Coupling and Contribution of Induced Orbital Angular Momentum of Low-Spin Fe^3+ Ions to Magnetic Anisotropy in Cyanide-Bridged Fe2M2 Molecular Magnets: Spin-Polarized Density-Functional Calculations, Physical Review B, Stephen Holmes and Kyungwha Park

Research from 2005

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Amyloid-β Protofibrils Differ from Amyloid-β Aggregates Induced in Dilute Hexafluoroisopropanol in Stability and Morphology, The Journal of Biological Chemistry, Michael Nichols, Melissa Moss, Dana Reed, Stephanie Cratic-McDaniel, Jan Hoh, and Terrone Rosenberry

Research from 2003

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Reactions of Boranes and Metallaboranes with Phosphines, Pure and Applied Chemistry, Lawrence Barton, Oleg Volkov, Mitsuhiro Hata, Paul McQuade, and Nigam Rath

Research from 1998

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2-Phenyl-3-(5,6,7,7a-tetrahydro-1H,3H-pyrrolo[1,2-c]oxazol-3-ylidene)-1-propene-1,1-dicarbonitrile and 4-(4-Methoxyphenyl)-2,6-bis(methylthio)pyridine-3-carbonitrile, Acta Crystallographica Section C-crystal Structure Communications, M. George, S. Das, C.V. Ashokan, N.P. Rath, and M.V. George

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Exo- and Endo-Tricarbonyl[(4b,5,6,7,8,8a-η)-Cis-N-Methyl-2,3,4,4a,9,9a-Hexahydro-1H- Carbazole]Chromium(0), Acta Crystallographica Section C: Crystal Structure Communications, Nigam Rath, F. Pigge, and Shiyue Fang

Research from 1997

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Dimethyl (±)-(1S*,2R*,3S*)-[3-Phenyl-1-(N-Phenylcarbamoyloxy)-2, 3-Epoxypropyl]-Phosphonate, Acta Crystallographica Section C-crystal Structure Communications, T. Boehlow, A. De La Cruz, N. Rath, and C. Spilling

Research from 1996

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[(CO)H(PPh3)2-Arachno-OsB3H8], Acta Crystallographica Section C: Crystal Structure Communications, Nigam Rath, J. Bould, and L. Barton